There are so many metabolic effects of caffeine that it has been hard to sort out which, exactly, are responsible for the increase in physical and mental energy that most users experience.
Caffeine is known to boost the effects of the neurotransmitters: serotonin, dopamine, and acetylcholine. Dopamine, for example, is known to affect levels of concentration. It blocks adenosine receptors in the basal forebrain, which when not impeded, are what typically signal the brain when it’s time to go to bed. Caffeine also increases the release of catecholamines (such as adrenaline) via the sympathetic nervous system, which among other things can make your heart beat faster, send more blood to your muscles, and tell your liver to release sugar into the bloodstream for energy.
Caffeine can help muscles to contract by encouraging the sarcoplasmic reticulum in muscle fibers to release calcium ions; it reduces the percentage of maximum exertion that a given exercise requires. Increasing circulating and intracellular substrate availability, or “fuel for the muscles”, occurs in response to changes brought on by caffeine, and may help to explain the perception of reduced exertion during exercise.
Based on scientific research, there are methods of enhancing the cognitive and energy-enhancing effects of caffeine while minimizing any negative physical impact. The synergy of caffeine combined with L-Theanine enhances performance without causing nervousness. L-Theanine has been recognized for its own ability to stimulate but in a calm way.
Researchers have found that the combination of caffeine and L-Theanine particularly improved speed and accuracy in tasks that required attention shifts. Participants also showed a reduced likelihood of being distracted during a memory task, which suggests that L Theanine and caffeine in combination are beneficial for improving performance on cognitively demanding tasks.
Vitamin B-12 is essential to energy production in the body. It is a nutrient you need for good health and is one of the eight B vitamins that help the body convert the food you eat into glucose, which gives you energy. Vitamin B-12 can, in some cases, reduce feelings of tiredness and weakness associated with anemia.